After installing Google Chrome on my home PC I noticed that I could only scroll down with my mouse wheel. When attempting to scroll up the browser did nothing. This seemed strange… since I could scroll up and down using the mouse wheel in other browsers (Safari, Firefox, IE).
This issue has been extensively discussed in forums across the internet. I found my fix in this sites discussion -> Solution to Google Chrome Mouse Scroll Issue
I ended up having to upgrade my mouse drivers from Microsofts site. I have a crazy old Microsoft Wheel Mouse Optical which is both cheap and effective.
Updated Microsoft mouse drivers can be downloaded from here: Microsoft Driver Download Site
Not only did upgrading the driver fix the issue, it also gave my mouse additional functionality. (Macro creation, better wheel manipulation capabilities etc.)
Google Chrome can be downloaded here: Download Google Chrome!
Scripthacks 